Symbol Name ID |
Otub1
OTU domain, ubiquitin aldehyde binding 1 MGI:2147616 |
Darker colors indicate more annotations |
Mouse Phenotypes | enlarged spleen |
decreased immature B cell number |
decreased B-1 B cell number |
increased mature B cell number |
increased B-2 B cell number |
increased marginal zone B cell number |
increased B cell number |
decreased T cell number |
abnormal follicular B cell morphology |
abnormal B cell activation |
increased IgA level |
increased IgG2a level |
increased IgG2b level |
increased IgM level |
increased immunoglobulin level |
increased circulating interleukin-6 level |
increased susceptibility to autoimmune disorder |
increased susceptibility to systemic lupus erythematosus |
increased anti-nuclear antigen antibody level |
increased anti-double stranded DNA antibody level |
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Availability | Mouse Genotype | ||||||||||||||||||||
Otub1tm1c(EUCOMM)Hmgu/Otub1tm1c(EUCOMM)Hmgu Cd19tm1(cre)Cgn/Cd19+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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